Dr. Weiss's career has focused on treatment and clinical research with substance-dependent patients. He has received numerous NIH grants developing integrated group therapy, an evidence-based treatment for co-occurring bipolar and substance use disorders; and leading a multi-site treatment study of prescription opioid dependence. He has authored over 300 publications, including several books, and was vice chair of the American Psychiatric Association Task Force on Practice Guidelines for Patients with Substance Use Disorders.
Dr. Weiss was named a member of honor by the Spanish Society for Dual Disorders in 2011; and has received numerous other awards, including the H. David Archibald Award for Outstanding Research and/or Practice in the Addictions from The Centre for Addiction and Mental Health in Toronto (2007), the Jack H. Mendelson Research Award from McLean Hospital (2012), and the Dan Anderson Research Award from the Hazelden Foundation (2012).
R. Kathryn McHugh, PhD
R. Kathryn McHugh, PhD Assistant Professor, Department of Psychiatry Harvard Medical School Associate Psychologist Division of Alcohol and Drug Abuse McLean Hospital Belmont, MA
Dr. R. Kathryn McHugh engages in a program of clinical and translational research focusing on the nature and treatment of anxiety and substance use disorders. She is particularly interested in the study of affective vulnerability factors, such as distress intolerance, that are common across psychological disorders, with a focus on those that can be modified with treatment. Additionally, Dr. McHugh conducts research on the dissemination and implementation of evidence-based treatments, with a particular focus on behavioral therapies.
Dr. McHugh is a recipient of awards from organizations such as the American Psychological Association and the College of Problems on Drug Dependence, and has received research funding from both local and national agencies, including a K23 Award from the National Institute on Drug Abuse. Dr. McHugh also specializes in cognitive behavioral therapy for depression, anxiety, and substance use disorders.
Charles P. O'Brien, MD, PhD
Charles P. O'Brien, MD, PhD Kenneth Appel Professor Department of Psychiatry University of Pennsylvania Philadelphia, PA
Dr. O'Brien received his MD and PhD degrees from Tulane University, and received residency training in psychiatry, neurology, and medicine at Harvard, the University of London, Tulane and the University of Pennsylvania (Penn). He is board-certified in psychiatry, neurology and addiction psychiatry.
One of the most prominent addiction researchers in the world, Dr. O'Brien has made many important discoveries and contributions over the past 30 years that have become the standard of care in addiction treatment throughout the world. Aside from developing medications to treat alcohol, opioid, and cocaine dependence, his work has also increased the understanding of the clinical aspects of addiction and the neurobiology of relapse.
Among his numerous honors, Dr. O'Brien was elected to the Institute of Medicine of the National Academy of Sciences in 1991, and received the Nathan B. Eddy award for research from the College on Problems of Drug Dependence in 2003. He has advised our national government on drug policy for decades, and was the President of the American College of Neuropsychopharmacology, and the Association for Research in Nervous and Mental Disease.
Dr. O'Brien is the Vice-Chair of Psychiatry at Penn, and the founding director of the prestigious Center for Studies of Addiction.
Opioid use disorder (OUD) is a prevalent and serious psychiatric illness with severe consequences, including death, if left untreated. Despite the availability of evidence-based treatment guidelines and medications that aid in the withdrawal from opioids and in long-term maintenance, OUD continues to be underdiagnosed and undertreated. Recent studies indicate that clinicians treating OUD lack understanding about the mechanisms of action (MOAs) of available medications to treat OUD, and how medication choice can influence patient adherence to treatment and clinical outcomes. The scenarios that follow describe and illustrate patient and disease-related considerations in medication-assisted treatment of OUD.
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Amanda Glazar, PhD
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