Managing Patients with Rheumatoid Arthritis After TNF Inhibitor or Methotrexate Failure


Managing Patients with Rheumatoid Arthritis After TNF Inhibitor or Methotrexate Failure

Topic: Rheumatology
Relevant Terms: rheumatology, rheumatoid arthritis
Primary Audience: This activity is intended for rheumatologists; PAs; NPs and nurses in rheumatology practices; and some internal medicine clinicians.
Launch Date: 14-Aug-18
Credits: AMA PRA Category 1 Credit
Expiration Date: 14-Aug-19
Curriculum Name: The Rheumatoid Arthritis Vital Education Initiative: New Horizons in Therapeutic Options (RAVE...

Learning Objectives

After completing this activity, the participant will demonstrate the ability to:

  1. Evaluate the role of IL-6 inhibiting therapies in patients with RA for whom methotrexate and anti-TNF medications have failed.
  2. Describe how the benefits of anti IL-6/IL-6R therapies may facilitate shared decision-making with patients and improve adherence.
  3. Address potential concerns about the anti IL-6/IL-6R safety profile to overcome patient barriers to treatment.


    Jonathan Samuels, MD
    Associate Professor of Medicine
    Division of Rheumatology
    NYU Langone Health
    New York, NY
    Roy Fleischmann, MD, MACR
    Co-Medical Director Metroplex Clinical Research Center
    Clinical Professor of Medicine
    University of Texas Southwestern Medical Center
    Dallas, TX
    Joint Accreditation Statement 
    In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and DKBmed, LLC. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
    Physician Continuing Medical Education
    The Postgraduate Institute for Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 
    Target Audience
    This activity is intended for rheumatologists, PAs, NPs and nurses in rheumatology practices, and some internal medicine clinicians.
    Educational Support 
    This activity is supported by an independent educational grant from Sanofi Genzyme and Regeneron Pharmaceuticals.

    Disclosure of Conflicts of Interest
    Postgraduate Institute for Medicine (PIM) requires instructors, planners, managers and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy.  PIM is committed to providing its learners with high quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest. The faculty reported no financial relationships or relationships they or their spouse/life partner have with commercial interests related to the content of this continuing education activity.

    Planners and Managers
    The PIM planners and managers have nothing to disclose.
    The following DKB planners and managers Stan Pogroszewski, and Lisa Alvarado hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.
    Disclosure of Unlabeled Use
    This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. 
    The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners.  Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
    Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.
    Jointly provided by Postgraduate Institute for Medicine and DKBmed, LLC.
    Estimated time to complete activity: 0.5 hours
    Method of Participating and Request for Credit
    There are no fees for participation in this CME activity. To receive credit, participants must 1) read the learning objectives and disclosure statements, 2) complete the educational activity and 3) complete the post-test and activity evaluation.
    Presented by PIM in collaboration with DKBmed
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